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What is Aloin? Aloin is an irritant laxative
contained in the yellow sap of Aloe, which is a constituent of the Anthraquinone Complex.As Dr. Ivan E. Danhof explains in his book 'Remarkable Aloe' ... 'Irritant laxatives, of which the anthraquinones
contained in the yellow sap of Aloe are examples, produce laxation by poisoning the enzyme systems in the intestinal wall which are responsible for the absorption of water and nutrients. Chronic laxative use
(laxative abuse) consists of chronic self-poisoning. It really cannot be recommended!' High amounts of Aloin will kill skin cells, as Dr. Danhof explains in his cell culture experiments described below. Cell Culture Experiments (Human Cell Medium M199 + 5% Human Serum)
Aloe Material |
Growth Response as a Percent of Control Human Fibroblasts |
Yellow Sap |
Total Kill |
Total Kill |
Total Kill |
Total Kill |
Concentration |
0.01 |
0.10 |
0.15 |
0.30 |
Internal Gel |
233% |
650% |
795% |
882% |
Cell Stimulation Factor |
2.33 |
6.50 |
7.95 |
8.82 |
'Perusal of the table shows that yellow sap at the four concentrations was highly toxic
to human fibroblasts in tissue culture. Not only was there no stimulation in fibroblast growth, but all the cells in the cultures were killed. By comparison, the control cells
(no yellow sap added) showed normal expected growth, which is rated at 100%. In contradistinction, when internal [Aloe] gel was added to the human fibroblasts in
tissue culture, stimulation of cell replication was evident at each of the four concentrations tested. At the lowest concentration of Aloe gel the number of cells
formed was more than twice the number of cells formed in the control (untreated) cultures. At the highest concentration of internal gel, the cell number increased nine-fold!' (Danhof 1984)
If certain levels of Aloin are also being legislated against, then surely it is prudent to use products from which the Aloin has effectively been removed. |